How A High-Fat Diet Disrupts Your Body Rhythm

A high-fat diet is not just bad for your heart, it also throws off your body rhythm or the internal body clock and interferes with metabolic functions in your body.


A study by Joe Bass, MD, Associate Professor of Medicine and Neurobiology and Physiology in Northwestern University in Chicago, USA published in the journal Cell Metabolism, looked at the relationship between the body clock and metabolism. The question is “Does food alter the body clock?” The answer is yes.

Joe Bass studied a group of genetically identical mice. They were fed a regular diet in the first two weeks. The mice were then split into two groups. For the next six weeks, one group of mice was fed a high-fat diet and another group was fed a regular diet. Both groups were kept in the dark, so that it was only the internal body clock that was controlling the metabolism.

The first group of mice that was fed a high-fat diet exhibited a shift in eating, activity, resting and sleeping patterns. They were eating during the normal sleeping time and consuming more calories compared to the second group of mice that were fed a regular diet. There was no change in behaviour in the second group of mice.

The high-fat diet altered the gene level, changing the timing of the gene switching on and off. This affected the chemicals coded by the gene, altering the metabolism in the organs and the cycle of activities.

On the other hand, if the high-fat diet is carefully scheduled, it can reduce body weight.

A study by Professor Oren Froy from the Institute of Biochemistry, Food Science & Nutrition, Hebrew University was published in FASED journal. This was an 18-week study on a group of mice fed on a high-fat diet dispensed at the same time and length of time, daily. One control group was fed on a low-fat diet without schedule and another control group was fed on an unscheduled high-fat diet.

After 18 weeks, the scheduled high-fat diet group of mice reduced in body weight compared to all the control groups. Even though the mice on a high-fat scheduled diet consumed the same calories as the mice on a low-fat unscheduled diet, the weight loss is higher.

This study suggested that timing and scheduled meals regulate the body clock and reduce the impact of a high-fat diet. A carefully scheduled high-fat diet can regulate the body’s metabolism to not store the fat but use it for energy when no food is available.

The study tells us that timing is everything. Eating a high-fat diet can affect your body clock and rhythm. However, if you time the meals properly, it can help to reduce the negative impact of the high-fat diet on the body.

Respect your body clock and you will prevent many health problems that arise with the disruption of the body rhythm.

 Visit Look Good Feel Great Always to find out more about Su Lee’s work.



This post was first published on Look Good Feel Great Always blog and has been reposted on Executive Lifestyle with the permission of the author.

Edited by Nedda Chaplin
Image credit: Asian Indian businessman eating food at cafeteria from Shutterstock


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Su Lee Chong

Su Lee Chong is the wellness coach and founder of Look Good Feel Great Always. She helps individuals to lose weight and provide corporate wellness programs to corporation through a holistic program of nutrition, exercise and knowledge. She is a trained chemist with more than 20 years experience in the specialty chemical industries ranging from coatings, household & personal care and food, holding various senior corporate positions. She uses her extensive knowledge in biochemistry of the human body to provide the knowledge and educate her clients on proper nutrition for the body. With the right knowledge, one is more likely to do the right action to achieve optimum health.

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